NMNH (β-Nicotinamide Mononucleotide Hydride), also known as Reduced NMN, is a reduced derivative of NMN (β-Nicotinamide Mononucleotide). As a high-performance biochemical raw material, its core function is to efficiently increase NAD+ (Nicotinamide Adenine Dinucleotide) levels in the body. With stability and bioavailability far superior to traditional NMN, its core effects include anti-aging and repair, metabolic regulation, and cell repair. It is widely used in high-end fields such as dietary supplements, cosmetics, and pharmaceutical intermediates, and is a core raw material for enterprises to upgrade their products to high-end.

I. Core Basic Information (Chemical Grade Standard)

Item	Specification Parameters	Remarks
Chinese Name	β-Nicotinamide Mononucleotide Reduced Form, Reduced NMN, NMNH	Unified industry designation, different from ordinary NMN
English Name	NMNH, β-Nicotinamide Mononucleotide Hydride	Suitable for international procurement scenarios
CAS No.	108347-85-9	Compliant with international chemical standards
Molecular Formula/Molecular Weight	C11H15N2Na2O8P/360.23	Ensures biological activity
Appearance	White to off-white crystalline powder, odorless, no visible impurities	Easy to dissolve and process
Purity Standard	≥99% (HPLC detection)	Compliant with dual standards of chemical grade and food grade
Solubility	Easily soluble in water and buffer, slightly soluble in ethanol, insoluble in ether	Optimal solubility at pH 5.5-7.0
Stability	Stable when sealed at room temperature; patented crystal form can be stable for 36 months	Superior to ordinary NMN, easy to store and transport
Heavy Metal Content	≤10ppm, impurities ≤0.1ppm (pharmaceutical grade)	Non-toxic and non-irritating, suitable for multiple scenarios

II. Chemical Structure and Core Characteristics

1.Chemical Structure

NMNH is modified from NMN by hydrogenation reduction, retaining the core skeleton of NMN and forming a stable reduced configuration. It can avoid oxidative degradation, maintain activity without complex modification, and quickly penetrate the cell membrane to enter cells, with significantly improved bioavailability, providing structural support for the exertion of its core effects.

2.Core Chemical Characteristics

• Strong Stability: Stable in the pH range of 4.0-8.0, not easy to degrade when sealed at room temperature, suitable for various formulas, ensuring long-lasting efficacy.
• Good Biocompatibility: Non-toxic and non-irritating, compliant with FDA GRAS standards, suitable for edible, external and other scenarios, and exerts effects safely.
• High Bioavailability: Can be directly absorbed by cells without metabolic conversion, the efficiency of increasing NAD+ is 10 times that of ordinary NMN, and the effect takes effect faster.
• Good Compatibility: Can synergize with coenzyme Q10, hyaluronic acid and other raw materials without antagonistic reaction, helping to superimpose effects.

III. Mechanism of Action, Core Effects and Application Fields

1.Core Mechanism of Action

As a high-efficiency NAD+ precursor, NMNH can quickly supplement NAD+ levels in the body, activate sirtuins, regulate autophagy, repair DNA damage, delay cell senescence, improve body metabolism, and assist tissue repair, providing core mechanism support for the exertion of effects.

2.Core Effects

• Anti-aging and Repair: Delays cell senescence, reduces oxidative damage, improves the body’s aging state, and at the same time can repair damaged skin barrier, reduce fine lines and brighten skin tone.
• Metabolic Regulation: Improves the efficiency of cellular energy metabolism, improves metabolic disorders, helps regulate blood sugar and blood lipids, relieves fatigue and enhances energy.
• Cell Repair: Promotes the repair and regeneration of damaged cells, assists wound healing and tissue repair, reduces scar formation, and protects organ function.

3. Main Application Fields

• Dietary Supplements: Used in anti-aging, metabolism-improving and energy-enhancing products, with an recommended addition amount of 0.1%-1.0%, suitable for various dosage forms.
• Pharmaceutical Intermediates: Used in the synthesis of tissue repair and anti-aging drugs, assisting wound healing and improving the aging state of organs.
• Cosmetics: Used in high-end anti-aging and repair products, promoting skin regeneration, repairing the barrier, and gently suitable for sensitive skin.
• Biological Repair: Used in scenarios such as post-medical beauty repair, conforming to the development demand of high efficiency and safety.

IV. Product Advantages (Factory Direct Supply)

• Controllable Purity: Adopting advanced technology, each batch is tested by HPLC, with purity ≥98%, high purity customizable, quality traceable, ensuring stable efficacy.
• Customized Services: Can provide different purities and packaging specifications, suitable for needs in multiple fields, supporting crystal form optimization to meet different efficacy requirements.
• Stable Supply Chain: Own production base, passed multiple international certifications, spot supply, reducing procurement costs and ensuring stable supply of functional raw materials.
• Compliance Guarantee: Complete qualifications, compliant with international standards, able to avoid patent risks, ensuring the legal and compliant use of functional raw materials.
• Technical Support: A professional team provides full-process guidance to help customers upgrade products and maximize the efficacy of NMNH.

V. Storage and Usage Instructions

1.Storage Conditions

• Powder: Store sealed, protected from light and dry at 2-8℃ (shelf life 24 months); storage at -20℃ can be extended to 36 months; patented crystal form can be stable for 36 months at room temperature to avoid efficacy loss.
• Solution: Can be stably stored at 4℃ for 7 days, and at -20℃ for 3 months when stored in aliquots; use as soon as possible after opening to prevent efficacy reduction.

2. Usage Notes

• Dissolution: Dissolve with sterile water, normal saline or buffer; it is recommended to add at ≤45℃ in the formula to avoid high temperature damaging the structure and affecting efficacy.
• Compatibility: Avoid mixing with strong acidic and strong oxidizing components to prevent efficacy reduction.
• Safety: Wear protective equipment during operation; prohibited for non-industrial, non-food and non-pharmaceutical use; strictly prohibited for direct consumption.

VI. Qualification and Testing

Our NMNH products have passed strict testing, and we can provide a full set of qualifications such as HPLC purity, nuclear magnetic resonance, heavy metal testing and FDA GRAS certification. They comply with industry standards in multiple fields, with controllable and traceable quality, passed multiple international certifications, ensuring both efficacy and safety.

With professional production, strict quality control and perfect after-sales service, we provide high-quality NMNH raw materials for global customers to help product upgrading and innovation!